Proteins are key elements in orchestrating almost every physiological
function that is required to survive, grow and thrive. If a specific
protein is absent or reduced in either quantity or function, a state
of serious disease can follow.
In the case of diabetes, the protein hormone insulin is lacking or
ineffective (either because the cells which produce insulin are
destroyed by the immune system, or because the body develops a
resistance to the effects of insulin).
In the 1920s our founders were successful in purifying and
mass-producing insulin in order to provide a well-tolerated and
effective treatment for diabetes, an otherwise deadly disease.
Since then, we have been further refining and improving our ability
to engineer, manufacture, purify and administer proteins for
the treatment of diabetes, obesity, NASH, rare blood disorders, rare
endocrine disorders, chronic kidney and cardiovascular disease, as
well as other diseases and conditions.