Gene technology ethics
Genetically modified organisms (GMOs) are living cells or organisms which have been genetically modified for research or to produce specific pharmaceutical substances. A gene coding for a recombinant protein is inserted into a DNA molecule carrying all the genetic elements necessary for the cell to produce the protein of interest. The assembled DNA carrying the genetic codes for the therapeutic protein is then inserted into the cells, enabling them to produce the recombinant protein.
Ethical implications of gene technology
Genetic modification of cells and organisms presents a unique opportunity to increase the possibility of offering safe and efficacious medical help for patients.
The use of gene technology in biomedical research and the use of GMOs in the production of pharmaceuticals offer substantial benefits to the quality of products, the environment and opportunities for the identification of new treatment concepts for patients.
Our position on gene technology
1 Contained use of gene technology
We find that the contained use of gene technology is an
important tool in the identification, development, and production of
pharmaceuticals for patients. These pharmaceuticals could not
otherwise be provided in sufficient quantity or quality.
2 Use of GMOs
We only use GMOs in the lowest risk category for production and
the final products do not contain genetically modified cells or genes.
3 Antibiotic resistance genes
We use production strains without antibiotic resistance genes
whenever technically possible and practically feasible.
4 Accidental release of GMOs
We recognise the concern about accidental release of GMOs to
the environment and has implemented appropriate measures to ensure
compliance with regulations set by the authorities.
5 Regulation and public concerns
We support the proper regulation of the use of gene technology
and the principle that public concerns are adequately addressed.
6 Precautionary principle
We apply the Precautionary Principle in the use of gene
technology by conducting risk assessments prior to use.
7 International standards
We actively participate in the development of relevant
international standards for gene technology.
8 Transparency and openness
We support transparency and openness in relation to the use of
gene technology and continues to report publicly on our use of the technology.
Gene technology ethics
The GMOs in use for research and production at Novo Nordisk are mainly microorganisms (i.e. fungi and bacteria) and mammalian cells.
Potential risks involved in the application of gene technology are thoroughly assessed at Novo Nordisk.
Over the years, we have developed modern insulins based on a new yeast strain, producing more product from each yeast cell.
Download our brochure about gene technology in medicine development and production.
