Long-acting a-MSH analogue

Alpha- melanocyte-stimulating hormone (a-MSH) is one of the native ligands for the melanocortin receptors 1-5. The melanocortin 4 receptor (MC4-R) is involved in the regulation of food intake and body weight. 

NNC0070-0453 is a long-acting MC4-R selective a-MSH analogue which is N-terminally modified with a long chain fatty acid derivative.