Type 1 diabetes is a lifelong disease that affects the body’s ability to convert glucose from food into energy. In most cases, type 1 diabetes develops early in life and is often diagnosed during childhood.
The disease starts when the immune system attacks cells in the pancreas that produce insulin, the hormone that helps convert glucose into energy for the body’s cells. Without daily injections of insulin, people living with type 1 would not be able to survive.
Based on almost 100 years of experience discovering and producing treatments for people with diabetes, our scientists are advancing research to reduce the number of insulin injections required to maintain good glycaemic control, and to prevent low blood glucose (hypoglycaemic) episodes.
Our ultimate goal is a cure for type 1 diabetes. We are progressing our research in regenerative medicine such as stem cell therapy, which may one day be used as a curative treatment of type 1 diabetes.
Meet Nic, who has type 1 diabetes, and hear about life with the disease.
Maintaining target blood glucose levels helps protect the body’s organs from damage. It also protects people living with type 1 diabetes from hypoglycaemia.
Insulin therapy aims to get as close as possible to the natural insulin response of someone without diabetes. This can help people living with type 1 diabetes maintain target blood glucose levels.
The closer insulin therapy gets to the body’s natural response, the better it is at balancing blood glucose levels.
Insulin treatment has evolved significantly, and with each advancement, we are closer to a natural insulin response. Most importantly, these advancements helped people living with type 1 diabetes overcome some of the inconveniences that come with treating and living with the disease.
One of our big ambitions is to develop glucose sensitive insulins that will eliminate hypoglycaemic events. This would be the next big breakthrough in type 1 diabetes care. We share this ambition with many partners in the diabetes research community and work closely with them towards a common goal – eliminating hypoglycaemia.
Meet Jacob Sten Petersen, Head of Stem Cell research, and hear his personal motivation to find a cure for type 1 diabetes.
Johnna Wesley, head of type 1 diabetes, immunology and kidney disease research