Chronic renal
disease
In children with progressive chronic renal disease (CRD), growth retardation is seen as a clinical manifestation in approximately one third of all cases.
The kidneys play a vital role in extracting waste products from the blood. In chronic renal disease, the kidneys fail to filter the blood properly. This creates an imbalance of growth factors in the blood, which leads to severe growth retardation in some patients.
Today, through dialysis and kidney transplantation, even children with end-stage renal failure are able to live long, fruitful lives. As a result, treatment for short stature has become an even greater need. Growth hormone therapy may help these children achieve normal height.
