Obesity has been recognised by health organisations including the WHO as a chronic disease that requires long-term management.1,2 Obesity has been identified as a health concern primarily due to its associated comorbidities and impact on quality of life. The risk of morbidity and mortality increases with the severity of obesity.15
Research has shown a weight loss of 5-10% in people with obesity can lead to significant health benefits.10,11
Due to the complex nature of obesity there is a need for multiple treatment options that can help people with obesity to lose weight, keep it off, and thereby improve their health.16
Building on our heritage as a world leader in diabetes care and other chronic diseases, Novo Nordisk are committed, long-term, to use our expertise to help people with obesity. For more information and resources about obesity and weight management, please visit our dedicated healthcare professional support website Rethink Obesity®.
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For more information about ongoing obesity research at Novo Nordisk please click here.
1. WHO. Obesity and Overweight Factsheet no. 311. Available at: http://www.who.int/mediacentre/factsheets/fs311/en/. Last accessed February 2016.
2. American Medical Association. A.M.A Adopts New Policies on Second Day of Voting at Annual Meeting. Obesity as a Disease. Available at: http://www.ama-assn.org/ama/pub/news/news/2013/2013-06-18-new-ama-policies-annual-meeting.page. Last accessed February 2016
3. Rosenbaum M, Kissileff HR, Mayer LE, et al. Energy intake in weight-reduced humans. Brain Res. 2010; 1350:95-102
4. Wright SM, Aronne LJ. Causes of obesity. Abdominal Imaging. 2012; 37:730-732
5. Pillar G, Shehadeh N. Abdominal fat and sleep apnea: the chicken or the egg? Diabetes Care. 2008; 31 Suppl 2:S303-309
6. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 2006; 444:840-846
7. National Cancer Institute at the National Institutes of Health. Obesity and Cancer Risk. http://www.cancer.gov/cancertopics/factsheet/Risk/obesity Last accessed February 2016.
8. Guh DP, Zhang W, Bansback N, et al. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009; 25:88
9. Puhl RM, Heuer CA. The stigma of obesity: a review and update. Obesity (Silver Spring). 2009; 17:941-964
10. Wing RR, Lang W, Wadden TA, et al. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care. 2011; 34:1481-1486
11. Dengo AL, Dennis EA, Orr JS, et al. Arterial destiffening with weight loss in overweight and obese middle-aged and older adults. Hypertension. 2010; 55:855-861
12. Sumithran P PL, Delbridge E, Purcell K, Shulkes A, Kriketos A, Proietto J. Long-term persistence of hormonal adaptations to weight loss. N Engl J Med. 2011; 365:1597-1604
13. Loureiro ML NRJ. Obesity, weight loss, and physician’s advice. . Soc Sci Med. 2006; 62:2458-2468
14. Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation. 2014; 129:S102-138
15. Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009; 373:1083-1096
16. Ferguson C, David S, Divine L, et al. Obesity Drug Outcome Measures - A Consensus Report of Considerations Regarding Pharmacologic Intervention https://publichealth.gwu.edu/pdf/obesitydrugmeasures.pdf 14 Aug 2012. Department of Health Policy,School of Public Health and Health Services, The George Washington University. Last accessed: April 2016.
At Novo Nordisk, we are committed to improving the understanding and management of obesity. Find out more about the science behind obesity and get resources to help with obesity and weight management at our healthcare professional support website Rethink Obesity®.