Tables

Table 7a. Novo Nordisk's products manufactured using genetic engineering

 

 

Pharmaceuticals

Application

GlucaGen®HypoKit

Hypoglycaemia

Human insulin

Diabetes

Norditropin®

Human growth
hormone deficiency

NovoSeven®

Haemophilia

 

 

Enzymes

Application

Alpha-GalTM

Animal Feed

AquazymTM Ultra

Textile Industry

Bio-FeedTM Wheat

Animal Feed

Carezyme®

Detergent Industry

Cellusoft® Ultra

Textile Industry

Denimax® Ultra

Textile Industry

DurazymTM

Detergent Industry

Greasex®

Leather Industry

Lipolase®

Detergent Industry

Lipolase Ultra

Detergent Industry

Lipozyme® IM

Interesterification

LiquozymeTM

Distilling Industry

Maltogenase®

Starch Industry

MaturexTM

Brewing Industry

Novamyl®

Baking Industry

NovoCorTMAD

Leather Industry and
Organic Synthesis

Novozym® 388

Organic Synthesis

Novozym 435

Ester Synthesis

Novozym 525

Organic Synthesis

Novozym 677

Baking Industry

PentopanTMMono

Baking Industry

PulpzymeTMHC

Pulp & Paper Industry

Relase®

Detergent Industry

Resinase®

Pulp & Paper Industry

Savinase®

Detergent Industry

Termamyl®

Starch, Detergent and
Textile Industries

ThermozymeTM

Textile Industry

Table 7b. Reduced consumption of resources from genetic engineering.
The figures state an index for consumption per metric ton of enzyme produced based on the conventional production organism.

Conventional microorganism Raw materials Water Steam Electricity

(weight) (weight) (weight) (kWh)
Fermentation 65 36 26 75
Recovery 35 64 74 25
TOTAL 100 100 100 100

Genetically-modified microorganism Raw materials Water Steam Electricity
Fermentation 32 18 13 38
Recovery 27 35 39 13
TOTAL 59 53 52 51
Percentage saved 41% 47% 48% 49%

Table 8. improved supply reliability from genetic engineering.
  1994 2004
Total world insulin requirement (million units) *162,000 **250,000
Total world insulin requirement (kg) 5,700 8,800
Yield after recovery (mg/kg pig glands) 100 100
Number of pig glands per kg 8 8
Number of pigs necessary to cover the world requirement
for insulin produced by the traditional method#
460,000,000 710,000,000

* Figures based on IMS (Intercontinental Medical Systems).
** Novo Nordiskšs estimate.
# For comparison, according to the Danish Meat Research Institute, worldwide production is approx. 1,300,000,000 pigs for slaughtering, but in practice only a fraction of this number is available due to decentralized slaughtering processes and long transport distances.

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